All Phenotypes Rnf213<tm1.1Kure> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf213^tm1.1Kure
targeted mutation 1.1, Shigeo Kure
MGI:5708305

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf213^tm1.1Kure/Rnf213^tm1.1Kure	Not Specified	MGI:5749136

Allelic Composition	Rnf213^tm1.1Kure/Rnf213^tm1.1Kure
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf213^tm1.1Kure mutation (0 available); any Rnf213 mutation (192 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal physiological neovascularization ( J:218591 )

• mice exhibit enhanced angiogenesis after femoral artery ligation compared to wild-type mice

homeostasis/metabolism

decreased susceptibility to injury ( J:218591 )

• blood flow recovery in the ischemic limb is improved in mutants, and mice exhibit milder ambulatory impairments and enhanced angiogenesis after femoral artery ligation compared to wild-type mice

• however, mice do not exhibit differences in infarct volume, edema formation or angiogenesis after transient middle cerebral artery occlusion compared to wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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