All Phenotypes Dhx30<Gt(IG)1Zsj> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dhx30^Gt(IG)1Zsj
gene trap 1, Zai-Si Ji
MGI:5705780

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dhx30^Gt(IG)1Zsj/Dhx30^Gt(IG)1Zsj	involves: 129S/SvEv * C57BL/6	MGI:5707721

Allelic Composition	Dhx30^Gt(IG)1Zsj/Dhx30^Gt(IG)1Zsj
Genetic Background	involves: 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx30^Gt(IG)1Zsj mutation (0 available); any Dhx30 mutation (104 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:218057 )

• no living homozygous embryos after E9.5

• some embryos still alive at E8.5

embryo

failure of initiation of embryo turning ( J:218057 )

• development through formation of head folds, heart, and allantois but embryos never turn

embryonic growth retardation ( J:218057 )

• E8.5 embryos similar in size to wild type E7.5 embryos

• mutant embryos are developmentally retarded at E7.5

abnormal neural tube morphology ( J:218057 )

• no neural tube

absent somites ( J:218057 )

• no organized somites

growth/size/body

embryonic growth retardation ( J:218057 )

• E8.5 embryos similar in size to wild type E7.5 embryos

• mutant embryos are developmentally retarded at E7.5

nervous system

abnormal neural tube morphology ( J:218057 )

• no neural tube

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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