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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Anxa8tm1Resc
targeted mutation 1, Ursula Rescher
MGI:5705281
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Anxa8tm1Resc/Anxa8tm1Resc
Tg(Pgk1-cre)1Lni/0 		involves: 129 * C57BL/6J * BALB/c MGI:5705287


Genotype
MGI:5705287
cn1
Allelic
Composition		 Anxa8tm1Resc/Anxa8tm1Resc
Tg(Pgk1-cre)1Lni/0
Genetic
Background		 involves: 129 * C57BL/6J * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anxa8tm1Resc mutation (0 available); any Anxa8 mutation (19 available)
Tg(Pgk1-cre)1Lni mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
impaired leukocyte tethering or rolling ( J:225224 )
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity

cellular
impaired leukocyte tethering or rolling ( J:225224 )
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity

hematopoietic system
impaired leukocyte tethering or rolling ( J:225224 )
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory