Analysis Tools
mortality/aging
|
• average lifespan is 57.3 weeks on average, shorter than in wild-type mice
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behavior/neurological
| N |
• mice exhibit normal performance on an accelerating rotarod at 14 weeks of age and do not exhibit clasping, kyphosis or impairments on the ledge test
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nervous system
| N |
• Purkinje cell dendritic arborization appears normal at 24 weeks of age
|
vision/eye
| N |
• retinas appear normal at 24 weeks of age and mice show normal ERG responses at 22 weeks of age
|
