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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Npy-EGFP/RNAi:Gad1)1Mirn
transgene insertion 1, Karoly Mirnics
MGI:5703795
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Npy-EGFP/RNAi:Gad1)1Mirn/? C57BL/6NHsd-Tg(Npy-EGFP/RNAi:Gad1)1Mirn MGI:5704096


Genotype
MGI:5704096
tg1
Allelic
Composition		 Tg(Npy-EGFP/RNAi:Gad1)1Mirn/?
Genetic
Background		 C57BL/6NHsd-Tg(Npy-EGFP/RNAi:Gad1)1Mirn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Npy-EGFP/RNAi:Gad1)1Mirn mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal behavioral response to amphetamine ( J:227900 )
• increased sensitivity to amphetamine-induced locomotion - 600% greater peak response as compared to controls
decreased anxiety-related response ( J:227900 )
• reduced anxiety like behavior in elevated zero maze and light-dark box
abnormal social investigation ( J:227900 )
• increased preference for social novelty (second stimulus mouse) versus familiar mouse in three chamber social task




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory