All Phenotypes Trp63<m1Mhda> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trp63^m1Mhda
mutation 1, Martin Hrabe de Angelis
MGI:5702898

Summary

2 genotypes

Allelic Composition	Trp63^m1Mhda/Trp63^m1Mhda
Genetic Background	C3HeB/FeJ-Trp63^m1Mhda

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63^m1Mhda mutation (1 available); any Trp63 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal craniofacial morphology ( J:82809 )

• "Darth Vader-like" appearance observed at embryonic day (E) 15

limbs/digits/tail

absent limbs ( J:82809 )

mortality/aging

Allelic Composition	Trp63^m1Mhda/Trp63⁺
Genetic Background	C3HeB/FeJ-Trp63^m1Mhda

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63^m1Mhda mutation (1 available); any Trp63 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:82809 )

• mice heterozygous for this mutation are viable and exhibit no obvious abnormality

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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