Phenotypes associated with this allele

• Allele Symbol: Kcnip1^tm1Zhzh
• Allele Name: targeted mutation 1, Zhuohua Zhang
• Allele ID: MGI:5702614
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnip1^tm1Zhzh/Kcnip1^tm1Zhzh	involves: C57BL/6	MGI:5702619

Genotype
MGI:5702619

hm1

• Allelic Composition: Kcnip1^tm1Zhzh/Kcnip1^tm1Zhzh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to induced morbidity/mortality ( J:227383 )

• pentylenetetrazole-treated mice exhibit increased incidence of seizure and death compared with wild-type mice

nervous system

nervous system phenotype ( J:227383 )

N • mice exhibit normal brain structure in the cerebellum, cortex and hippocampus

increased susceptibility to pharmacologically induced seizures ( J:227383 )

• pentylenetetrazole-treated mice exhibit increased incidence of seizure and death compared with wild-type mice

• however, untreated homozygotes do not show any seizures under normal housing conditions

behavior/neurological

increased susceptibility to pharmacologically induced seizures ( J:227383 )

• pentylenetetrazole-treated mice exhibit increased incidence of seizure and death compared with wild-type mice

• however, untreated homozygotes do not show any seizures under normal housing conditions