All Phenotypes Tg(Npy2r-cre)1Tfur MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Npy2r-cre)1Tfur
transgene insertion 1, Takahisa Furukawa
MGI:5701375

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ift80^{tm1c(KOMP)Wtsi}/Ift80^{tm1c(KOMP)Wtsi} Tg(Npy2r-cre)1Tfur/0	involves: C3H * C57BL/6JJcl * C57BL/6N	MGI:5701514

Allelic Composition	Ift80^{tm1c(KOMP)Wtsi}/Ift80^{tm1c(KOMP)Wtsi} Tg(Npy2r-cre)1Tfur/0
Genetic Background	involves: C3H * C57BL/6JJcl * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift80^{tm1c(KOMP)Wtsi} mutation (1 available); any Ift80 mutation (56 available)
Tg(Npy2r-cre)1Tfur mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal motile cilium morphology ( J:226948 )

• the number of Npy2r+ cilia in the hypothalamic arcuate nucleus is decreased compared to in control mice

• however, mice exhibit normal numbers of Adcy3+ cilia in the hypothalamic arcuate nucleus

growth/size/body

increased body weight ( J:226948 )

• at 19 weeks

• however, weight at 13 weeks is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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