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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pop4em1Mvw
endonuclease-mediated mutation 1, Michael Wiles
MGI:5700023
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pop4em1Mvw/Pop4em1Mvw B6(C3Fe)-Pop4em1Mvw/MvwJ MGI:5700026
ht2
 		Pop4em1Mvw/Pop4+ B6(C3Fe)-Pop4em1Mvw/MvwJ MGI:5700027


Genotype
MGI:5700026
hm1
Allelic
Composition		 Pop4em1Mvw/Pop4em1Mvw
Genetic
Background		 B6(C3Fe)-Pop4em1Mvw/MvwJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pop4em1Mvw mutation (1 available); any Pop4 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:227249 )
• no homozygotes were identified from multiple heterozygous intercrosses and no increase in perinatal pup loss was found indicating complete prenatal lethality




Genotype
MGI:5700027
ht2
Allelic
Composition		 Pop4em1Mvw/Pop4+
Genetic
Background		 B6(C3Fe)-Pop4em1Mvw/MvwJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pop4em1Mvw mutation (1 available); any Pop4 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:227249 )
• heterozygotes are viable and fertile with no obvious phenotypic abnormalities




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory