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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir203tm1.2Yir
targeted mutation 1.2, Rui Yi
MGI:5698456
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mir203tm1.2Yir/Mir203tm1.2Yir B6(Cg)-Mir203tm1.2Yir MGI:5698463


Genotype
MGI:5698463
hm1
Allelic
Composition
Mir203tm1.2Yir/Mir203tm1.2Yir
Genetic
Background
B6(Cg)-Mir203tm1.2Yir
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir203tm1.2Yir mutation (0 available); any Mir203 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• treated mice exhibit 2.5 fold more tumors than treated controls, although there is no statistically significant in tumor size

integument
• increase in skin thickness of E16 embryos
• thickness is most prominent at E16 and E17, but becomes comparable to control by P4

neoplasm
• treated mice exhibit 2.5 fold more tumors than treated controls, although there is no statistically significant in tumor size
• earlier onset of tumor formation following chemical carcinogenesis as compared to controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory