Phenotypes associated with this allele

• Allele Symbol: Ccnc^tm1.2Pisc
• Allele Name: targeted mutation 1.2, Piotr Sicinski
• Allele ID: MGI:5697678
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccnc^tm1.2Pisc/Ccnc^tm1.2Pisc	Not Specified	MGI:5697680

Genotype
MGI:5697680

hm1

• Allelic Composition: Ccnc^tm1.2Pisc/Ccnc^tm1.2Pisc
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal cell cycle ( J:217695 )

• mutant cells presented a defect in cell cycle re-entry from quiescence, especially when stimulated with lower concentrations of serum

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:217695 )

• mice died in utero at embryonic day 10.5

embryo

embryonic growth retardation ( J:217695 )

• severe developmental retardation of mutant embryos

placental labyrinth hypoplasia ( J:217695 )

• underdeveloped placental labyrinth layer

growth/size/body

embryonic growth retardation ( J:217695 )

• severe developmental retardation of mutant embryos