All Phenotypes Ccnc<tm1.2Pisc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ccnc^tm1.2Pisc
targeted mutation 1.2, Piotr Sicinski
MGI:5697678

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccnc^tm1.2Pisc/Ccnc^tm1.2Pisc	Not Specified	MGI:5697680

Allelic Composition	Ccnc^tm1.2Pisc/Ccnc^tm1.2Pisc
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnc^tm1.2Pisc mutation (0 available); any Ccnc mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell cycle ( J:217695 )

• mutant cells presented a defect in cell cycle re-entry from quiescence, especially when stimulated with lower concentrations of serum

mortality/aging

• mice died in utero at embryonic day 10.5

embryo

embryonic growth retardation ( J:217695 )

• severe developmental retardation of mutant embryos

placental labyrinth hypoplasia ( J:217695 )

• underdeveloped placental labyrinth layer

growth/size/body

embryonic growth retardation ( J:217695 )

• severe developmental retardation of mutant embryos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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