Phenotypes associated with this allele

• Allele Symbol: B3gat3^tm1Hkit
• Allele Name: targeted mutation 1, Hiroshi Kitagawa
• Allele ID: MGI:5697553
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	B3gat3^tm1Hkit/B3gat3^tm1Hkit	involves: 129P2/OlaHsd * C57BL/6J	MGI:5697557

Genotype
MGI:5697557

hm1

• Allelic Composition: B3gat3^tm1Hkit/B3gat3^tm1Hkit
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation ( J:225032 )

• most homozygous mutant embryos die before E2.5 (8-cell stage)

homeostasis/metabolism

abnormal glycosaminoglycan level ( J:225032 )

• reduction of the synthesis of chondroitin sulfate and heparan sulfate glycosaminoglycans in homozygous embryos

cellular

abnormal mitotic cytokinesis ( J:225032 )

• incomplete cytokinesis observed at 2-4 cell stage division of mutant embryos