Phenotypes associated with this allele

• Allele Symbol: Arf1^tm1.1Towa
• Allele Name: targeted mutation 1.1, Toshio Watanabe
• Allele ID: MGI:5697481
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arf1^tm1.1Towa/Arf1^tm1.1Towa	involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj	MGI:5697504

Genotype
MGI:5697504

hm1

• Allelic Composition: Arf1^tm1.1Towa/Arf1^tm1.1Towa
• Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:220201 )

• abnormal (degenerated) homozygous embryos were observed at E5.5 and were not found at later stages

• empty implantation sites are found at later stages

• homozygous mutant blastocysts were indistinguishable from that of controls at E3.5

• after 7 days of culture, both mutant and control blastocysts produced the same trophectoderm (TE) outgrowths and inner cell mass (ICM); there were no differences in the mean ICM ratio (ICM area/TE area) between mutant and control cultured blastocysts.