Phenotypes associated with this allele

• Allele Symbol: Tg(ATXN2*72Q)#Plt
• Allele Name: transgene insertion, Stefan M Pulst
• Allele ID: MGI:5697198
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(ATXN2*72Q)#Plt/0	FVB/N-Tg(ATXN2*72Q)#Plt	MGI:5697200

Genotype
MGI:5697200

tg1

• Allelic Composition: Tg(ATXN2*72Q)#Plt/0
• Genetic Background: FVB/N-Tg(ATXN2*72Q)#Plt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired coordination ( J:224692 )

• performance on the accelerating rotarod becomes worse starting at 16 weeks of age and mice perform poorly with age

growth/size/body

decreased body size ( J:224692 )

• smaller body size beginning at 8 weeks of age

decreased body weight ( J:224692 )

• mice weigh about 30% less than wild-type mice by 24 week of age

nervous system

abnormal Purkinje cell morphology ( J:224692 )

• Purkinje cell morphological changes at 24 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
spinocerebellar ataxia 2		DOID:0050955	OMIM:183090	J:224692