All Phenotypes D130043K22Rik<tm1b(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

D130043K22Rik^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5696928

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik^{tm1b(KOMP)Wtsi}	C57BL/6N-D130043K22Rik^{tm1b(KOMP)Wtsi}/Ucd	MGI:6262244
hm2	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik^{tm1b(KOMP)Wtsi}	involves: C57BL/6 * CBA	MGI:6112643
ht3	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik⁺	involves: C57BL/6 * CBA	MGI:6112644

Allelic Composition	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-D130043K22Rik^{tm1b(KOMP)Wtsi}/Ucd
Cell Lines	EPD0077_5_D04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Rik^{tm1b(KOMP)Wtsi} mutation (1 available); any D130043K22Rik mutation (57 available)

Data Sources

IMPC Data for D130043K22Rik

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased mean corpuscular volume ( J:211773 )

IMPC - UCD

Allelic Composition	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik^{tm1b(KOMP)Wtsi}
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Rik^{tm1b(KOMP)Wtsi} mutation (1 available); any D130043K22Rik mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:241324 )

N	• activity in 1-hour open field test • social interaction and response to social novelty in 3-chamber apparatus • locomotor behavior and motor coordination and balance • spatial learning, working memory and reference memory • learning, memory and conditioning

decreased anxiety-related response ( J:241324 )

• spending more time in light area in light/dark box test

cellular

cellular phenotype ( J:241324 )

N	• cell cycle and mitosis in embryonic brain at E15.5 and E18.5

nervous system

nervous system phenotype ( J:241324 , J:241324 )

N	• radial glial cell number in brain at E15.5 and E18.5 (J:241324) • cortical wall thickness in telencephalon at E18.5 (J:241324) • telencephalon, cortical plate, dentate gyrus and hippocampus CA1 region morphology at P2 and P10 (J:241324) • cerebellum morphology at E15.5, E18.5 and P10 (J:241324)
N	• prepulse inibition (J:241324)

increased prepulse inhibition ( J:241324 )

• in startle responses at long intervals between prepulse and acoustic startle-eliciting stimulus

Allelic Composition	D130043K22Rik^{tm1b(KOMP)Wtsi}/D130043K22Rik⁺
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Rik^{tm1b(KOMP)Wtsi} mutation (1 available); any D130043K22Rik mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:241324 )

N	• activity in 1-hour open field test • social interaction and response to social novelty in 3-chamber apparatus • locomotor behavior and motor coordination and balance • spatial learning, working memory and reference memory • learning, memory and conditioning • anxiety related response

nervous system

nervous system phenotype ( J:241324 )

N	• radial glial cell number in brain at E15.5 and E18.5 • cortical wall thickness in telencephalon at E18.5 • telencephalon, cortical plate, dentate gyrus and hippocampus CA1 region morphology at P2 and P10 • cerebellum morphology at E15.5, E18.5 and P10 • prepulse inibition

cellular

cellular phenotype ( J:241324 )

N	• cell cycle and mitosis in embryonic brain at E15.5 and E18.5

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