Phenotypes associated with this allele

• Allele Symbol: Med1^{tm3b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 3b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5696880
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Med1^tm3b(EUCOMM)Wtsi/Med1^tm3b(EUCOMM)Wtsi	C57BL/6N-Med1^tm3b(EUCOMM)Wtsi/Tcp	MGI:6288569
ht2	Med1^tm3b(EUCOMM)Wtsi/Med1^+	C57BL/6N-Med1^tm3b(EUCOMM)Wtsi/Tcp	MGI:6288568

Genotype
MGI:6288569

hm1

• Allelic Composition: Med1^{tm3b(EUCOMM)Wtsi}/Med1^{tm3b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Med1^{tm3b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0934_5_F01

Data Sources

IMPC Data for Med1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal placenta size ( J:211773 )

♂

IMPC - TCP

pale yolk sac ( J:211773 )

♂

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

IMPC - TCP

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - TCP

Genotype
MGI:6288568

ht2

• Allelic Composition: Med1^{tm3b(EUCOMM)Wtsi}/Med1⁺
• Genetic Background: C57BL/6N-Med1^{tm3b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0934_5_F01

Data Sources

IMPC Data for Med1

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

nervous system

small superior vagus ganglion ( J:211773 )

♀

IMPC - UCD

reproductive system

enlarged uterus ( J:211773 )

♀

IMPC - UCD

hydrometra ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD