Phenotypes associated with this allele

• Allele Symbol: Alkbh1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5695126
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Alkbh1^tm1b(EUCOMM)Hmgu/Alkbh1^tm1b(EUCOMM)Hmgu	C57BL/6N-Alkbh1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6261847
ht2	Alkbh1^tm1b(EUCOMM)Hmgu/Alkbh1^+	C57BL/6N-Alkbh1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6261846

Genotype
MGI:6261847

hm1

• Allelic Composition: Alkbh1^{tm1b(EUCOMM)Hmgu}/Alkbh1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Alkbh1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0751_6_G08

Data Sources

IMPC Data for Alkbh1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6261846

ht2

• Allelic Composition: Alkbh1^{tm1b(EUCOMM)Hmgu}/Alkbh1⁺
• Genetic Background: C57BL/6N-Alkbh1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0751_6_G08

Data Sources

IMPC Data for Alkbh1

digestive/alimentary system

abnormal ileum morphology ( J:211773 )

♂

IMPC - HMGU

endocrine/exocrine glands

abnormal mammary gland morphology ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

increased plasmacytoid dendritic cell number ( J:211773 )

♀

IMPC - HMGU

decreased Ly6C-positive NK T cell number ( J:211773 )

♀

IMPC - HMGU

abnormal spleen morphology ( J:211773 )

♂

IMPC - HMGU

immune system

increased plasmacytoid dendritic cell number ( J:211773 )

♀

IMPC - HMGU

decreased Ly6C-positive NK T cell number ( J:211773 )

♀

IMPC - HMGU

abnormal spleen morphology ( J:211773 )

♂

IMPC - HMGU

enlarged lymph nodes ( J:211773 )

IMPC - HMGU

integument

abnormal mammary gland morphology ( J:211773 )

♀

IMPC - HMGU

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - HMGU

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - HMGU