Phenotypes associated with this allele

• Allele Symbol: Rft1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692864
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rft1^tm1b(KOMP)Wtsi/Rft1^tm1b(KOMP)Wtsi	C57BL/6N-Rft1^tm1b(KOMP)Wtsi/Bay	MGI:6263363
ht2	Rft1^tm1b(KOMP)Wtsi/Rft1^+	C57BL/6N-Rft1^tm1b(KOMP)Wtsi/Bay	MGI:6263362

Genotype
MGI:6263363

hm1

• Allelic Composition: Rft1^{tm1b(KOMP)Wtsi}/Rft1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Rft1^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0707_2_E09

Data Sources

IMPC Data for Rft1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6263362

ht2

• Allelic Composition: Rft1^{tm1b(KOMP)Wtsi}/Rft1⁺
• Genetic Background: C57BL/6N-Rft1^{tm1b(KOMP)Wtsi}/Bay
• Cell Lines: EPD0707_2_E09

Data Sources

IMPC Data for Rft1

hematopoietic system

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - HAR

increased hemoglobin content ( J:211773 )

♀

IMPC - HAR

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - HAR

increased mean corpuscular volume ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

increased monocyte cell number ( J:211773 )

♂

IMPC - HAR

immune system

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

increased monocyte cell number ( J:211773 )

♂

IMPC - HAR

limbs/digits/tail

long tibia ( J:211773 )

♀

IMPC - HAR

skeleton

long tibia ( J:211773 )

♀

IMPC - HAR