Phenotypes associated with this allele

• Allele Symbol: Pfdn5^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692755
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pfdn5^tm1b(EUCOMM)Wtsi/Pfdn5^tm1b(EUCOMM)Wtsi	C57BL/6N-Pfdn5^tm1b(EUCOMM)Wtsi/Bay	MGI:6263144
ht2	Pfdn5^tm1b(EUCOMM)Wtsi/Pfdn5^+	C57BL/6N-Pfdn5^tm1b(EUCOMM)Wtsi/Bay	MGI:6288644

Genotype
MGI:6263144

hm1

• Allelic Composition: Pfdn5^{tm1b(EUCOMM)Wtsi}/Pfdn5^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Pfdn5^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0242_1_C04

Data Sources

IMPC Data for Pfdn5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

♀

IMPC - BCM

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - BCM

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - BCM

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

homeostasis/metabolism

edema ( J:211773 )

♀

IMPC - BCM

integument

abnormal skin coloration ( J:211773 )

♀

IMPC - BCM

limbs/digits/tail

abnormal tail morphology ( J:211773 )

♀

IMPC - BCM

mortality/aging

prenatal lethality ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6288644

ht2

• Allelic Composition: Pfdn5^{tm1b(EUCOMM)Wtsi}/Pfdn5⁺
• Genetic Background: C57BL/6N-Pfdn5^{tm1b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0242_1_C04

Data Sources

IMPC Data for Pfdn5

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - BCM

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - BCM