Phenotypes associated with this allele

• Allele Symbol: Gpbp1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692726
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gpbp1^tm1b(EUCOMM)Wtsi/Gpbp1^tm1b(EUCOMM)Wtsi	C57BL/6N-Gpbp1^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262555
ht2	Gpbp1^tm1b(EUCOMM)Wtsi/Gpbp1^+	C57BL/6N-Gpbp1^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262554

Genotype
MGI:6262555

hm1

• Allelic Composition: Gpbp1^{tm1b(EUCOMM)Wtsi}/Gpbp1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Gpbp1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0783_5_A09

Data Sources

IMPC Data for Gpbp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262554

ht2

• Allelic Composition: Gpbp1^{tm1b(EUCOMM)Wtsi}/Gpbp1⁺
• Genetic Background: C57BL/6N-Gpbp1^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0783_5_A09

Data Sources

IMPC Data for Gpbp1

behavior/neurological

abnormal gait ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

shortened PR interval ( J:211773 )

♂

IMPC - HMGU

shortened PQ interval ( J:211773 )

♂

IMPC - HMGU

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♀

IMPC - HMGU

improved glucose tolerance ( J:211773 )

IMPC - HMGU

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU