Phenotypes associated with this allele

• Allele Symbol: Tmem161b^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692723
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem161b^tm2b(EUCOMM)Hmgu/Tmem161b^tm2b(EUCOMM)Hmgu	C57BL/6N-Tmem161b^tm2b(EUCOMM)Hmgu/Bay	MGI:6263711
ht2	Tmem161b^tm2b(EUCOMM)Hmgu/Tmem161b^+	C57BL/6N-Tmem161b^tm2b(EUCOMM)Hmgu/Bay	MGI:6263710

Genotype
MGI:6263711

hm1

• Allelic Composition: Tmem161b^{tm2b(EUCOMM)Hmgu}/Tmem161b^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Tmem161b^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0809_5_C07

Data Sources

IMPC Data for Tmem161b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - HAR

embryo

abnormal embryo size ( J:211773 )

IMPC - HAR

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - HAR

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6263710

ht2

• Allelic Composition: Tmem161b^{tm2b(EUCOMM)Hmgu}/Tmem161b⁺
• Genetic Background: C57BL/6N-Tmem161b^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0809_5_C07

Data Sources

IMPC Data for Tmem161b

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

decreased circulating total protein level ( J:211773 )

♀

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR