Phenotypes associated with this allele

• Allele Symbol: Pdss2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692707
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdss2^tm1b(EUCOMM)Hmgu/Pdss2^tm1b(EUCOMM)Hmgu	C57BL/6N-Pdss2^tm1b(EUCOMM)Hmgu/H	MGI:5767755
ht2	Pdss2^tm1b(EUCOMM)Hmgu/Pdss2^+	C57BL/6N-Pdss2^tm1b(EUCOMM)Hmgu/H	MGI:5797703

Genotype
MGI:5767755

hm1

• Allelic Composition: Pdss2^{tm1b(EUCOMM)Hmgu}/Pdss2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Pdss2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0711_7_A08

Data Sources

IMPC Data for Pdss2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797703

ht2

• Allelic Composition: Pdss2^{tm1b(EUCOMM)Hmgu}/Pdss2⁺
• Genetic Background: C57BL/6N-Pdss2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0711_7_A08

Data Sources

IMPC Data for Pdss2

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

behavior/neurological

decreased anxiety-related response ( J:211773 )

IMPC - HAR

decreased thigmotaxis ( J:211773 )

IMPC - HAR

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

hematopoietic system

thrombocytopenia ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - HAR

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - HAR

vertebral fusion ( J:211773 )

♂

IMPC - HAR