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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkg1tm1b(KOMP)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5692576
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkg1tm1b(KOMP)Wtsi/Prkg1tm1b(KOMP)Wtsi C57BL/6N-Prkg1tm1b(KOMP)Wtsi/H MGI:5797736
ht2
 		Prkg1tm1b(KOMP)Wtsi/Prkg1+ C57BL/6N-Prkg1tm1b(KOMP)Wtsi/H MGI:6263234


Genotype
MGI:5797736
hm1
Allelic
Composition		 Prkg1tm1b(KOMP)Wtsi/Prkg1tm1b(KOMP)Wtsi
Genetic
Background		 C57BL/6N-Prkg1tm1b(KOMP)Wtsi/H
Cell Lines EPD0553_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkg1tm1b(KOMP)Wtsi mutation (1 available); any Prkg1 mutation (65 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system

growth/size/body
enlarged spleen ( J:211773 )
IMPC - HAR

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - HAR

immune system
enlarged spleen ( J:211773 )
IMPC - HAR

mortality/aging




Genotype
MGI:6263234
ht2
Allelic
Composition		 Prkg1tm1b(KOMP)Wtsi/Prkg1+
Genetic
Background		 C57BL/6N-Prkg1tm1b(KOMP)Wtsi/H
Cell Lines EPD0553_5_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkg1tm1b(KOMP)Wtsi mutation (1 available); any Prkg1 mutation (65 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system
enlarged heart ( J:211773 )
IMPC - HAR

growth/size/body
enlarged heart ( J:211773 )
IMPC - HAR




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory