All Phenotypes Lama5<tm1b(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lama5^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5692561

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lama5^{tm1b(KOMP)Wtsi}/Lama5^{tm1b(KOMP)Wtsi}	C57BL/6N-Lama5^{tm1b(KOMP)Wtsi}/H	MGI:5757302
ht2	Lama5^{tm1b(KOMP)Wtsi}/Lama5⁺	C57BL/6N-Lama5^{tm1b(KOMP)Wtsi}/H	MGI:5757301
ht3	Lama5^mpc205H/Lama5^{tm1b(KOMP)Wtsi}	involves: BALB/c * C3H/HeH * C57BL/6J * C57BL/6N	MGI:8250774

Allelic Composition	Lama5^{tm1b(KOMP)Wtsi}/Lama5^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Lama5^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0179_1_C10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama5^{tm1b(KOMP)Wtsi} mutation (0 available); any Lama5 mutation (157 available)

Data Sources

IMPC Data for Lama5

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Lama5^{tm1b(KOMP)Wtsi}/Lama5⁺
Genetic Background	C57BL/6N-Lama5^{tm1b(KOMP)Wtsi}/H
Cell Lines	EPD0179_1_C10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama5^{tm1b(KOMP)Wtsi} mutation (0 available); any Lama5 mutation (157 available)

Data Sources

IMPC Data for Lama5

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

enlarged heart ( J:211773 )

IMPC - HAR

growth/size/body

enlarged heart ( J:211773 )

IMPC - HAR

Allelic Composition	Lama5^mpc205H/Lama5^{tm1b(KOMP)Wtsi}
Genetic Background	involves: BALB/c * C3H/HeH * C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama5^mpc205H mutation (1 available); any Lama5 mutation (157 available)
Lama5^{tm1b(KOMP)Wtsi} mutation (0 available); any Lama5 mutation (157 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating creatinine level ( J:344185 )

• increased plasma creatinine levels at 22 weeks of age

increased blood urea nitrogen level ( J:344185 )

• increased plasma urea levels at 22 weeks of age

decreased circulating serum albumin level ( J:344185 )

• decreased plasma albumin levels at 22 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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