Phenotypes associated with this allele

• Allele Symbol: Gcdh^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692549
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gcdh^tm2b(EUCOMM)Hmgu/Gcdh^tm2b(EUCOMM)Hmgu	C57BL/6N-Gcdh^tm2b(EUCOMM)Hmgu/Bay	MGI:6288474
ht2	Gcdh^tm2b(EUCOMM)Hmgu/Gcdh^+	C57BL/6N-Gcdh^tm2b(EUCOMM)Hmgu/Bay	MGI:6262503

Genotype
MGI:6288474

hm1

• Allelic Composition: Gcdh^{tm2b(EUCOMM)Hmgu}/Gcdh^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gcdh^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0802_2_A06

Data Sources

IMPC Data for Gcdh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart left ventricle size ( J:211773 )

♀

IMPC - BCM

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - BCM

decreased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - BCM

decreased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - BCM

decreased circulating total protein level ( J:211773 )

♂

IMPC - BCM

integument

abnormal coat appearance ( J:211773 )

IMPC - BCM

abnormal skin coloration ( J:211773 )

♂

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♀

IMPC - BCM

Genotype
MGI:6262503

ht2

• Allelic Composition: Gcdh^{tm2b(EUCOMM)Hmgu}/Gcdh⁺
• Genetic Background: C57BL/6N-Gcdh^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0802_2_A06

Data Sources

IMPC Data for Gcdh

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - BCM