Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IkbkbM1Btlr mutation
(0 available);
any
Ikbkb mutation
(54 available)
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immune system
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• mice exhibit an increase in the CD4+ to CD8+ T cell ratio caused by a diminished frequency of peripheral CD8+ T cells in CD3 T cells after MCMV infection
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• some mice exhibit a reduced frequency of B1a cells in B1 cells and an increased frequency of B1b cells in B1 cells
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hematopoietic system
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• mice exhibit an increase in the CD4+ to CD8+ T cell ratio caused by a diminished frequency of peripheral CD8+ T cells in CD3 T cells after MCMV infection
|
|
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• some mice exhibit a reduced frequency of B1a cells in B1 cells and an increased frequency of B1b cells in B1 cells
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IkbkbM1Btlr mutation
(0 available);
any
Ikbkb mutation
(54 available)
|
|
|
immune system
|
|
• mice exhibit an increase in the CD4+ to CD8+ T cell ratio caused by a diminished frequency of peripheral CD8+ T cells in CD3 T cells after MCMV infection
|
|
|
• some mice exhibit a reduced frequency of B1a cells in B1 cells and an increased frequency of B1b cells in B1 cells in the peripheral blood after MCMV infection
|
|
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• after MCMV infection, mice exhibit an increase in the CD4+ to CD8+ T cell ratio caused by a diminished frequency of peripheral CD8+ T cells in CD3 T cells and some mice exhibit a reduced frequency of B1a cells in B1 cells and an increased frequency of B1b cells in B1 cells in the peripheral blood
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• mice exhibit impaired IgE and IgG1 responses to the cysteine protease papain
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hematopoietic system
|
|
• mice exhibit an increase in the CD4+ to CD8+ T cell ratio caused by a diminished frequency of peripheral CD8+ T cells in CD3 T cells after MCMV infection
|
|
|
• some mice exhibit a reduced frequency of B1a cells in B1 cells and an increased frequency of B1b cells in B1 cells in the peripheral blood after MCMV infection
|
Analysis Tools