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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nos3m1Btlr
mutation 1, Bruce Beutler
MGI:5691955
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nos3m1Btlr/Nos3m1Btlr C57BL/6J-Nos3m1Btlr MGI:5692063


Genotype
MGI:5692063
hm1
Allelic
Composition		 Nos3m1Btlr/Nos3m1Btlr
Genetic
Background		 C57BL/6J-Nos3m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos3m1Btlr mutation (0 available); any Nos3 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment

growth/size/body
increased susceptibility to weight loss ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment

immune system
increased susceptibility to induced colitis ( J:225268 )
• mice are susceptible to low doses of DSS (1%) and show weight loss seven days after DSS treatment




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory