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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zap70m3Btlr
mutation 3, Bruce Beutler
MGI:5690199
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zap70m3Btlr/Zap70m3Btlr C57BL/6J-Zap70m3Btlr MGI:5691378


Genotype
MGI:5691378
hm1
Allelic
Composition		 Zap70m3Btlr/Zap70m3Btlr
Genetic
Background		 C57BL/6J-Zap70m3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zap70m3Btlr mutation (0 available); any Zap70 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased IgG level ( J:225043 )
• mice showed diminished T-dependent antibody responses to ovalbumin administered with aluminum hydroxide and recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFVbeta-gal)

immune system
decreased IgG level ( J:225043 )
• mice showed diminished T-dependent antibody responses to ovalbumin administered with aluminum hydroxide and recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFVbeta-gal)
impaired humoral immune response ( J:225043 )
• mice showed diminished T-dependent antibody responses to ovalbumin administered with aluminum hydroxide and recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFVbeta-gal)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory