All Phenotypes Fasl<m2Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fasl^m2Btlr
mutation 2, Bruce Beutler
MGI:5688496

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fasl^m2Btlr/Fasl^m2Btlr	C57BL/6J-Fasl^m2Btlr	MGI:5688547

Allelic Composition	Fasl^m2Btlr/Fasl^m2Btlr
Genetic Background	C57BL/6J-Fasl^m2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasl^m2Btlr mutation (0 available); any Fasl mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgG level ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

impaired humoral immune response ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system

decreased IgG level ( J:224659 )

• mice exhibited diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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