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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Grm7m1Btlr
mutation 1, Bruce Beutler
MGI:5688492
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Grm7m1Btlr/Grm7m1Btlr C57BL/6J-Grm7m1Btlr MGI:5688559


Genotype
MGI:5688559
hm1
Allelic
Composition		 Grm7m1Btlr/Grm7m1Btlr
Genetic
Background		 C57BL/6J-Grm7m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm7m1Btlr mutation (0 available); any Grm7 mutation (124 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperresponsive to tactile stimuli ( J:224658 )
• mice are hypersensitive to touch after the seizure when scruffing was attempted again for the next minute
convulsive seizures ( J:224658 )
• some mice exhibited shaking behavior upon scruffing
• some mice also exhibited unilateral forepaw contractions that generalized and resolved within 30 seconds

nervous system
convulsive seizures ( J:224658 )
• some mice exhibited shaking behavior upon scruffing
• some mice also exhibited unilateral forepaw contractions that generalized and resolved within 30 seconds




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory