Phenotypes associated with this allele

• Allele Symbol: Stox2^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5661957
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stox2^tm2b(EUCOMM)Hmgu/Stox2^tm2b(EUCOMM)Hmgu	C57BL/6N-Stox2^tm2b(EUCOMM)Hmgu/J	MGI:6263598
ht2	Stox2^tm2b(EUCOMM)Hmgu/Stox2^+	C57BL/6N-Stox2^tm2b(EUCOMM)Hmgu/J	MGI:6263597

Genotype
MGI:6263598

hm1

• Allelic Composition: Stox2^{tm2b(EUCOMM)Hmgu}/Stox2^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Stox2^{tm2b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0837_2_B04

Data Sources

IMPC Data for Stox2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263597

ht2

• Allelic Composition: Stox2^{tm2b(EUCOMM)Hmgu}/Stox2⁺
• Genetic Background: C57BL/6N-Stox2^{tm2b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0837_2_B04

Data Sources

IMPC Data for Stox2

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased fasting circulating glucose level ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - JAX