Phenotypes associated with this allele

• Allele Symbol: Tg(Myh6-Jup)2Ajm
• Allele Name: transgene insertion 2, Ali J Marian
• Allele ID: MGI:5660502
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-Jup)2Ajm/0	involves: FVB/N	MGI:5660503

Genotype
MGI:5660503

tg1

• Allelic Composition: Tg(Myh6-Jup)2Ajm/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:192719 )

• increase in mortality

cardiovascular system

abnormal heart morphology ( J:192719 )

• increase in the number of adipocytes in the heart, with predominant distribution in the epicardium and patchy adipocyte distribution in the myocardium

cardiac interstitial fibrosis ( J:192719 )

• interstitial fibrosis is increased about 2-fold

abnormal heart echocardiography feature ( J:192719 )

• modest increase in left ventricular end diastolic diameter, but normal left ventricular end systolic diameter and left ventricular fractional shortening

adipose tissue

abnormal fat cell morphology ( J:192719 )

• increase in the number of adipocytes in the heart, with predominant distribution in the epicardium and patchy adipocyte distribution in the myocardium

cellular

cardiac interstitial fibrosis ( J:192719 )

• interstitial fibrosis is increased about 2-fold