Phenotypes associated with this allele

• Allele Symbol: Mc4r^{tm3.1(cre)Lowl}
• Allele Name: targeted mutation 3.1, Bradford B Lowell
• Allele ID: MGI:5647881
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gpr45^em2Zz/Gpr45^em2Zz Mc4r^tm3.1(cre)Lowl/Mc4r^+	involves: 129S6/SvEvTac * C57BL/6	MGI:8216705

Genotype
MGI:8216705

cn1

• Allelic Composition: Gpr45^em2Zz/Gpr45^em2Zz; Mc4r^{tm3.1(cre)Lowl}/Mc4r⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:367505 )

• mice exhibit increased body weight, fat weight and lean weight at 16 weeks of age

increased susceptibility to diet-induced obesity ( J:367505 )

• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight

homeostasis/metabolism

increased susceptibility to diet-induced obesity ( J:367505 )

• mice fed a high-fat diet starting at 6 weeks of age and maintained for 4 weeks exhibit increased body weight and fat weight