Phenotypes associated with this allele

• Allele Symbol: Stxbp1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5645993
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stxbp1^tm1b(EUCOMM)Hmgu/Stxbp1^tm1b(EUCOMM)Hmgu	C57BL/6N-Stxbp1^tm1b(EUCOMM)Hmgu/J	MGI:6263605
ht2	Stxbp1^tm1b(EUCOMM)Hmgu/Stxbp1^+	C57BL/6N-Stxbp1^tm1b(EUCOMM)Hmgu/J	MGI:6263604

Genotype
MGI:6263605

hm1

• Allelic Composition: Stxbp1^{tm1b(EUCOMM)Hmgu}/Stxbp1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Stxbp1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0510_5_H11

Data Sources

IMPC Data for Stxbp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263604

ht2

• Allelic Composition: Stxbp1^{tm1b(EUCOMM)Hmgu}/Stxbp1⁺
• Genetic Background: C57BL/6N-Stxbp1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0510_5_H11

Data Sources

IMPC Data for Stxbp1

behavior/neurological

increased exploration in new environment ( J:211773 )

♀

IMPC - JAX

increased thigmotaxis ( J:211773 )

IMPC - JAX

increased grip strength ( J:211773 )

♂

IMPC - JAX

hyperactivity ( J:211773 )

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

hematopoietic system

decreased hematocrit ( J:211773 )

♂

IMPC - JAX

increased mean corpuscular volume ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - JAX