Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Magohtm1c(KOMP)Dlsi mutation
(0 available);
any
Magoh mutation
(15 available)
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normal phenotype
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• homozygotes are viable and fertile with no overt phenotype
• no microcephalic phenotype is observed
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Krj mutation
(2 available);
any
Emx1 mutation
(34 available)
Magohtm1c(KOMP)Dlsi mutation
(0 available);
any
Magoh mutation
(15 available)
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nervous system
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• at P12, mutant mice exhibit significantly smaller brains than heterozygous Emx1tm1(cre)Krj control mice
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• at E16.5, cortical thickness is significantly reduced relative to wild-type controls, but thicker than in mice heterozygous for the MagohMos2 allele (likely due to a contribution of ventrally derived neurons which migrate into the dorsal telencephalon, but are not targeted by Emx1-Cre)
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|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1(cre)Krj mutation
(2 available);
any
Emx1 mutation
(34 available)
Magohtm1c(KOMP)Dlsi mutation
(0 available);
any
Magoh mutation
(15 available)
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Analysis Tools
