Phenotypes associated with this allele

• Allele Symbol: Nadk2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5637034
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nadk2^tm1b(EUCOMM)Wtsi/Nadk2^tm1b(EUCOMM)Wtsi	C57BL/6N-Nadk2^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5767735
ht2	Nadk2^tm1b(EUCOMM)Wtsi/Nadk2^+	C57BL/6N-Nadk2^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5797667

Genotype
MGI:5767735

hm1

• Allelic Composition: Nadk2^{tm1b(EUCOMM)Wtsi}/Nadk2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Nadk2^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0638_1_A06

Data Sources

IMPC Data for Nadk2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

Genotype
MGI:5797667

ht2

• Allelic Composition: Nadk2^{tm1b(EUCOMM)Wtsi}/Nadk2⁺
• Genetic Background: C57BL/6N-Nadk2^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0638_1_A06

Data Sources

IMPC Data for Nadk2

integument

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - WTSI

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - WTSI