Phenotypes associated with this allele

• Allele Symbol: Eif2b3^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5636947
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eif2b3^tm1b(EUCOMM)Hmgu/Eif2b3^tm1b(EUCOMM)Hmgu	C57BL/6N-Eif2b3^tm1b(EUCOMM)Hmgu/H	MGI:5757036
ht2	Eif2b3^tm1b(EUCOMM)Hmgu/Eif2b3^+	C57BL/6N-Eif2b3^tm1b(EUCOMM)Hmgu/H	MGI:5757035

Genotype
MGI:5757036

hm1

• Allelic Composition: Eif2b3^{tm1b(EUCOMM)Hmgu}/Eif2b3^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Eif2b3^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0728_3_D09

Data Sources

IMPC Data for Eif2b3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757035

ht2

• Allelic Composition: Eif2b3^{tm1b(EUCOMM)Hmgu}/Eif2b3⁺
• Genetic Background: C57BL/6N-Eif2b3^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0728_3_D09

Data Sources

IMPC Data for Eif2b3

hematopoietic system

decreased hemoglobin content ( J:211773 )

IMPC - HAR

decreased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - HAR