Phenotypes associated with this allele

• Allele Symbol: Ift81^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636927
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ift81^tm1b(EUCOMM)Wtsi/Ift81^tm1b(EUCOMM)Wtsi	C57BL/6N-Ift81^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262677
ht2	Ift81^tm1b(EUCOMM)Wtsi/Ift81^+	C57BL/6N-Ift81^tm1b(EUCOMM)Wtsi/Ieg	MGI:6262676

Genotype
MGI:6262677

hm1

• Allelic Composition: Ift81^{tm1b(EUCOMM)Wtsi}/Ift81^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ift81^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0382_4_F06

Data Sources

IMPC Data for Ift81

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262676

ht2

• Allelic Composition: Ift81^{tm1b(EUCOMM)Wtsi}/Ift81⁺
• Genetic Background: C57BL/6N-Ift81^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0382_4_F06

Data Sources

IMPC Data for Ift81

behavior/neurological

increased startle reflex ( J:211773 )

♀

IMPC - HMGU

decreased grip strength ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

decreased heart rate ( J:211773 )

IMPC - HMGU

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU