Phenotypes associated with this allele

• Allele Symbol: Npat^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636907
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npat^tm1b(EUCOMM)Wtsi/Npat^tm1b(EUCOMM)Wtsi	C57BL/6N-Npat^tm1b(EUCOMM)Wtsi/Wtsi	MGI:5767743

Genotype
MGI:5767743

hm1

• Allelic Composition: Npat^{tm1b(EUCOMM)Wtsi}/Npat^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Npat^{tm1b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0370_4_H05

Data Sources

IMPC Data for Npat

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

persistent trigeminal artery ( J:239583 )

DMDD

abnormal vertebral artery origin ( J:239583 )

DMDD

abnormal vertebral artery topology ( J:239583 )

DMDD

symmetric azygos veins ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

abnormal atrioventricular cushion morphology ( J:239583 )

DMDD

double outlet right ventricle ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

digestive/alimentary system

abnormal intestine placement ( J:239583 )

DMDD

embryo

abnormal Mullerian duct morphology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal testis morphology ( J:239583 )

DMDD

growth/size/body

thoracoschisis ( J:239583 )

DMDD

fetal growth retardation ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

limbs/digits/tail

abnormal humerus morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal infrahyoid muscle morphology ( J:239583 )

DMDD

abnormal digastric muscle morphology ( J:239583 )

DMDD

nervous system

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

small superior cervical ganglion ( J:239583 )

DMDD

reduced sympathetic cervical ganglion size ( J:239583 )

DMDD

renal/urinary system

abnormal ureter topology ( J:239583 )

DMDD

double ureter ( J:239583 )

DMDD

reproductive system

abnormal testis morphology ( J:239583 )

DMDD

respiratory system

abnormal infrahyoid muscle morphology ( J:239583 )

DMDD

abnormal digastric muscle morphology ( J:239583 )

DMDD

skeleton

abnormal humerus morphology ( J:239583 )

DMDD

rib fusion ( J:239583 )

DMDD

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

retrolental blood ( J:239583 )

DMDD