Phenotypes associated with this allele

• Allele Symbol: Pygo2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5636261
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pygo2^tm1b(EUCOMM)Wtsi/Pygo2^tm1b(EUCOMM)Wtsi	C57BL/6N-Pygo2^tm1b(EUCOMM)Wtsi/Tcp	MGI:6288684
ht2	Pygo2^tm1b(EUCOMM)Wtsi/Pygo2^+	C57BL/6N-Pygo2^tm1b(EUCOMM)Wtsi/Tcp	MGI:6288683

Genotype
MGI:6288684

hm1

• Allelic Composition: Pygo2^{tm1b(EUCOMM)Wtsi}/Pygo2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Pygo2^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0767_1_C03

Data Sources

IMPC Data for Pygo2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - TCP

craniofacial

abnormal craniofacial morphology ( J:211773 )

♀

IMPC - TCP

embryo

abnormal neural tube closure ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube closure ( J:211773 )

♂

IMPC - TCP

abnormal midbrain morphology ( J:211773 )

♂

IMPC - TCP

abnormal hindbrain morphology ( J:211773 )

♂

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - TCP

microphthalmia ( J:211773 )

IMPC - TCP

anophthalmia ( J:211773 )

IMPC - TCP

Genotype
MGI:6288683

ht2

• Allelic Composition: Pygo2^{tm1b(EUCOMM)Wtsi}/Pygo2⁺
• Genetic Background: C57BL/6N-Pygo2^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0767_1_C03

Data Sources

IMPC Data for Pygo2

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - UCD