Phenotypes associated with this allele

• Allele Symbol: Trmt1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5634291
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trmt1^tm1b(EUCOMM)Hmgu/Trmt1^tm1b(EUCOMM)Hmgu	C57BL/6N-Trmt1^tm1b(EUCOMM)Hmgu/Ics	MGI:5757829
ht2	Trmt1^tm1b(EUCOMM)Hmgu/Trmt1^+	C57BL/6N-Trmt1^tm1b(EUCOMM)Hmgu/Ics	MGI:5767833

Genotype
MGI:5757829

hm1

• Allelic Composition: Trmt1^{tm1b(EUCOMM)Hmgu}/Trmt1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Trmt1^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0743_6_A06

Data Sources

IMPC Data for Trmt1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5767833

ht2

• Allelic Composition: Trmt1^{tm1b(EUCOMM)Hmgu}/Trmt1⁺
• Genetic Background: C57BL/6N-Trmt1^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0743_6_A06

Data Sources

IMPC Data for Trmt1

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - ICS

prolonged QRS complex duration ( J:211773 )

♀

IMPC - ICS

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♂

IMPC - ICS

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - ICS

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - ICS

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - ICS

vision/eye

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - ICS

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - ICS