Analysis Tools
immune system
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• mice with this mutation exhibit decreased TNFalpha secretion in response to the TLR9 ligand CpG oligodeoxynucleotide; secretion is lower in homozygous than in heterozygous mutant mice.
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Allele Symbol Allele Name Allele ID |
Tlr9M9Btlr mutation 9, Bruce Beutler MGI:5632141 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice with this mutation exhibit decreased TNFalpha secretion in response to the TLR9 ligand CpG oligodeoxynucleotide; secretion is lower in homozygous than in heterozygous mutant mice.
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice with this mutation exhibit decreased TNFalpha secretion in response to the TLR9 ligand CpG oligodeoxynucleotide; secretion in heterozygous mutant mice is intermediate between that of wild-type and homozygous mutants.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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