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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnq2tm3.1Snhr
targeted mutation 3.1, Shinichi Hirose
MGI:5629465
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcnq2tm3.1Snhr/Kcnq2tm3.1Snhr B6.Cg-Kcnq2tm3.1Snhr MGI:5703899
ht2
 		Kcnq2tm3.1Snhr/Kcnq2+ B6.Cg-Kcnq2tm3.1Snhr MGI:5703900


Genotype
MGI:5703899
hm1
Allelic
Composition		 Kcnq2tm3.1Snhr/Kcnq2tm3.1Snhr
Genetic
Background		 B6.Cg-Kcnq2tm3.1Snhr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnq2tm3.1Snhr mutation (0 available); any Kcnq2 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:213443 )
• all homozygotes die shortly after birth




Genotype
MGI:5703900
ht2
Allelic
Composition		 Kcnq2tm3.1Snhr/Kcnq2+
Genetic
Background		 B6.Cg-Kcnq2tm3.1Snhr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnq2tm3.1Snhr mutation (0 available); any Kcnq2 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
clonic seizures ( J:213443 )
• increased seizure severity compared to controls after PTZ injection

nervous system
clonic seizures ( J:213443 )
• increased seizure severity compared to controls after PTZ injection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory