All Phenotypes Ntrk1<tm1.1Jcar> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ntrk1^tm1.1Jcar
targeted mutation 1.1, Juan C Arevalo
MGI:5620208

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ntrk1^tm1.1Jcar/Ntrk1^tm1.1Jcar	involves: 129S1/Sv * C57BL/6	MGI:5688680

Allelic Composition	Ntrk1^tm1.1Jcar/Ntrk1^tm1.1Jcar
Genetic Background	involves: 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk1^tm1.1Jcar mutation (0 available); any Ntrk1 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:219326 )

N	• mice are viable and fertile with a normal life span

nervous system

abnormal sensory neuron physiology ( J:219326 )

• in culture, DRG neurons obtained from E13.5 mutant embryos exhibit enhanced NGF-mediated signaling and increased cell survival in limiting amounts of NGF relative to wild-type neurons

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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