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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		H2-Ab1g7-em1Ygch
endonuclease-mediated mutation 1, Yi-Guang Chen
MGI:5618308
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		H2-Ab1g7-em1Ygch/H2-Ab1g7-em1Ygch NOD/ShiLtJ-H2-Ab1g7-em1Ygch MGI:5618334


Genotype
MGI:5618334
hm1
Allelic
Composition		 H2-Ab1g7-em1Ygch/H2-Ab1g7-em1Ygch
Genetic
Background		 NOD/ShiLtJ-H2-Ab1g7-em1Ygch
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-Ab1g7-em1Ygch mutation (1 available); any H2-Ab1 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:101977 )
• mice exhibit greatly reduced numbers of CD4 single positive T cells in the thymus and spleen

immune system
decreased CD4-positive, alpha-beta T cell number ( J:101977 )
• mice exhibit greatly reduced numbers of CD4 single positive T cells in the thymus and spleen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory