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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Clcn2tm2.1Tjj
targeted mutation 2.1, Thomas J Jentsch
MGI:5618265
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Clcn2tm2.1Tjj/Clcn2tm2.1Tjj involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5646506
cx2
 		Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Hepacamtm1.2Tjj/Hepacamtm1.2Tjj 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac MGI:5646507


Genotype
MGI:5646506
hm1
Allelic
Composition		 Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clcn2tm2.1Tjj mutation (0 available); any Clcn2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:210308 )
N
• no myelin vacuolization is seen at 17 weeks of age




Genotype
MGI:5646507
cx2
Allelic
Composition		 Clcn2tm2.1Tjj/Clcn2tm2.1Tjj
Hepacamtm1.2Tjj/Hepacamtm1.2Tjj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clcn2tm2.1Tjj mutation (0 available); any Clcn2 mutation (40 available)
Hepacamtm1.2Tjj mutation (0 available); any Hepacam mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelin sheath morphology ( J:210308 )
• myelin vacuolization is increased compared to either single homozygote




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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory