About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr35tm1.1Lap
targeted mutation 1.1, Len Pennacchio
MGI:5616933
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr35tm1.1Lap/Rr35tm1.1Lap involves: 129S6/SvEvTac * C57BL/6J MGI:6107682


Genotype
MGI:6107682
hm1
Allelic
Composition		 Rr35tm1.1Lap/Rr35tm1.1Lap
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr35tm1.1Lap mutation (1 available); any Rr35 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal myocardial fiber morphology ( J:252154 )
• disarray with enlarged nucleus
decreased cardiac muscle contractility ( J:252154 )
• modest decrease in fractional shortening and ejection fraction

growth/size/body
growth/size/body region phenotype ( J:252154 )
N
• mice exhibit normal growth

muscle
abnormal myocardial fiber morphology ( J:252154 )
• disarray with enlarged nucleus
decreased cardiac muscle contractility ( J:252154 )
• modest decrease in fractional shortening and ejection fraction




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory