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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr34tm1.1Lap
targeted mutation 1.1, Len Pennacchio
MGI:5616932
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr34tm1.1Lap/Rr34tm1.1Lap involves: 129S6/SvEvTac * C57BL/6J MGI:6107681


Genotype
MGI:6107681
hm1
Allelic
Composition		 Rr34tm1.1Lap/Rr34tm1.1Lap
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr34tm1.1Lap mutation (1 available); any Rr34 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal myocardial fiber morphology ( J:252154 )
• disarray with enlarged nucleus
decreased cardiac muscle contractility ( J:252154 )
• modest decrease in fractional shortening and ejection fraction

growth/size/body
decreased body weight ( J:252154 )
• in female, but no male, mice

muscle
abnormal myocardial fiber morphology ( J:252154 )
• disarray with enlarged nucleus
decreased cardiac muscle contractility ( J:252154 )
• modest decrease in fractional shortening and ejection fraction




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory