About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Irf7M2Btlr
mutation 2, Bruce Beutler
MGI:5615723
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Irf7M2Btlr/Irf7M2Btlr C57BL/6J-Irf7M2Btlr MGI:5615978
ht2
 		Irf7M2Btlr/Irf7+ C57BL/6J-Irf7M2Btlr MGI:5615979


Genotype
MGI:5615978
hm1
Allelic
Composition		 Irf7M2Btlr/Irf7M2Btlr
Genetic
Background		 C57BL/6J-Irf7M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf7M2Btlr mutation (0 available); any Irf7 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA

immune system
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA




Genotype
MGI:5615979
ht2
Allelic
Composition		 Irf7M2Btlr/Irf7+
Genetic
Background		 C57BL/6J-Irf7M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf7M2Btlr mutation (0 available); any Irf7 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA

immune system
decreased circulating interferon-beta level ( J:217798 )
• after stimulation with double stranded (ds) DNA




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory