Phenotypes associated with this allele

• Allele Symbol: Sirpa^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5614693
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sirpa^tm1b(EUCOMM)Hmgu/Sirpa^tm1b(EUCOMM)Hmgu	C57BL/6N-Sirpa^tm1b(EUCOMM)Hmgu/Bay	MGI:5813029

Genotype
MGI:5813029

hm1

• Allelic Composition: Sirpa^{tm1b(EUCOMM)Hmgu}/Sirpa^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Sirpa^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0880_5_A03

Data Sources

IMPC Data for Sirpa

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

hematopoietic system

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

homeostasis/metabolism

decreased blood urea nitrogen level ( J:211773 )

♀

IMPC - BCM

impaired glucose tolerance ( J:211773 )

♀

IMPC - BCM

immune system

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - BCM

vision/eye

abnormal retina outer nuclear layer morphology ( J:211773 )

IMPC - BCM